We are using high-resolution 3D imaging to visualize developmental morphologies and processes in embryos of model and non-model species. MicroCT imaging produces size-calibrated volume images with histological resolutions, and the volume images can be imported into other software for segmentation and analysis. Our research efforts include establishing new tools for morphological and morphometric studies of patterning and function, methods for statistical analysis of 3D forms, and methods for quantitative 3D imaging of molecular patterns.
We are always interested in discussing new imaging applications and possible collaborations.
Herdina AN, Kelly DA, Jahelková H, Lina PHC, Horáček I, Metscher BD (2015) Testing hypotheses of bat baculum function with 3D models derived from microCT. Journal of Anatomy 226(3):229-235
Mayer C, Metscher BD, Müller GB, Mitteroecker P (2014) Studying developmental variation with geometric morphometric image analysis (GMIA). PLoS ONE 9(12): e115076
Schulz-Mirbach T, Ladich F, Plath M, Metscher BD, Heß M (2014) Are accessory hearing structures linked to inner ear morphology? Insights from 3D orientation patterns of ciliary bundles in three cichlid species. Frontiers in Zoology 11:25
Metscher BD (2013) Biological applications of X-ray microtomography: imaging micro-anatomy, molecular expression and organismal diversity. Microscopy and Analysis 27(2): 13-16
Schulz-Mirbach T, Hess M, Metscher BD (2013) Sensory epithelia of the fish inner ear in 3D: studied with high-resolution contrast enhanced microCT. Frontiers in Zoology 10:63.