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The Theoretical Biology MicroCT Imaging Lab

We are applying x-ray microtomographic imaging (microCT) to a variety ofresearch problems in development and evolution, including comparative embryology, functional morphology, and morphometric studies. We are not a service facility, but we are interested in discussing productive collaborations.

The lab has two microCT scanning systems, both self-contained (i.e. no synchrotron source). The big one is a  MicroXCT model manufactured by Xradia, Inc., capable of tomographic imaging of biological objects from about 5mm down to less than 500µm in size, with possible resolutions below 2µm. The smaller scanner is a SkyScan 1174 for lower resolution imaging of larger specimens. This is a low-cost scanner made for samples up to about 30mm, and gives spatial resolutions down to about 20µm. 

Some recent publications about or featuring microCT imaging:

Metscher, B. D. 2013. Biological applications of X-ray microtomography: imaging micro-anatomy, molecular expression and organismal diversity. Microscopy and Analysis 27 (2):13-16.

Sandholzer, M. A., Baron, K., Heimel, P., and Metscher, B. D. 2013. Volume analysis of heat-induced cracks in human molars: A preliminary study. Journal of Forensic Dental Sciences, in press.

Karolyi, F., Morawetz, L., Colville, J. F., Handschuh, S., Metscher, B. D., and Krenn, H. W. 2013. Time management and nectar flow: flower handling and suction feeding in long-proboscid flies (Nemestrinidae: Prosoeca). Naturwissenschaften in press.

Schulz-Mirbach, T., Heß, M., Metscher, B. D., and Ladich, F. 2013. A unique swim bladder-inner ear connection in a teleost fish revealed by a combined high-resolution microCT and 3D histological study. BMC Biology 2013, 11:75. http://www.biomedcentral.com/1741-7007/11/75   

Kerbl, A., Handschuh, S., Nödl, M.-T., Metscher, B., Walzl, M., and Wanninger, A. 2013. Micro-CT in cephalopod research: Investigating the internal anatomy of a sepiolid squid using a non-destructive technique with special focus on the ganglionic system. J Exp Mar Biol Ecol, 447:140-148. http://dx.doi.org/10.1016/j.jembe.2013.02.022

Schulz-Mirbach, T., Metscher, B., and Ladich, F. 2012. Relationship between Swim Bladder Morphology and Hearing Abilities: Case Study on Asian and African Cichlids. PLoS ONE 7 (8):e42292. http://dx.doi.org/10.1371%2Fjournal.pone.0042292

Zimmermann, D., Randolf, S., Metscher, B. D., and Aspöck, U. 2011. The function and phylogenetic implications of the tentorium in adult Neuroptera (Insecta). Arthropod Struct Dev 40:571-582. http://dx.doi.org/10.1016/j.asd.2011.06.003

Briguglio, A., Metscher, B., and Hohenegger, J. 2011. Growth Rate Biometric Quantification by X- ray Microtomography on Larger Benthic Foraminifera: Three-dimensional Measurements push Nummulitids into the Fourth Dimension. Turkish J. Earth Sci. 20:683-699. http://mistug.tubitak.gov.tr/bdyim/abs.php?dergi=yer&rak=0910-44

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